probably a configuration error, when you say " I LOOSE ALL SOUND!" that is a good thing it means that the device is detected and attempting to route sound outputs via the audio box and not through whatever you were listening to before
you didnt really provide information on what you have plugged in where, what operating system you are using, if you are monitoring via the audiobox or another interface - you need to be a lot clearer instead of just complaining if you want people to help you out
I am usually a windows guy but i took my 2009 mbp out for a spin this weekend as my other rig was in use somewhere else. I recorded as usual using a belkin 800 to 400 cable that i know is good. Performers complained to me after abo. ut 15 minutes the in ear. mixers were clicking i ended up having to disconnect the mac and problem went away. Last night i did further testing with the mac. Turns out i have to run in safe mode 1 or 2 to stop the glitching it is noticeable in the audio recordings as a rubber banding effect. The mac is a decent spec i7 2.7ghz 8gb ram with 480gb ssd it has no problems running with audiobox or pod500hd and no other software was running
Macos 10.7.4
Studio one 2.0.7
Sorry about grammar lol i typed this on my phone, i wish this forum had phone support!!